Written by and starring The Comeback and Hacks’ Dan Bucatinsky and featuring a rich ensemble cast that includes Richard Ruccolo, Sasha Alexander, Adam Goldberg, Christina Ricci, Andrea Martin, Doris Roberts, and Lisa Kudrow, All Over the Guy is a hilarious rom-com about a mismatched pair of gay men set up on a blind date by their mutual straight friends. Come revisit the Closing Night film of Frameline25 on the big screen again!

Gay chaos ensues when groom-to-be John Michael (Cole Doman) reunites with his best man and old flame Alex (Michael Hsu Rosen) at a lakeside bachelor party weekend that draws the whole wedding party into the drama. Joined by mischievous duo, Luís and Simon, and hunky, bisexual Kit, this quartet of college pals have a time, stir up some mayhem, and find true love in this cheeky rom-com.

Suddenly dumped by his boyfriend and totally broke, Nate crawls to the only people that will take him, his sweet, offbeat grandparents, played by Academy Award winner F. Murray Abraham and Caroline Aaron who welcome him to their lovely Jewish old folk’s home. Fueled by amusing energy, colorful characters and unique setting, the film digs deeper with big questions about identity and belonging.

Fresh off of winning the Audience Award at Frameline49 with Castration Movie Anthology i. Traps, Louise Weard returns to the Festival with the latest chapter in her epic-in-the-making anthology film series, putting her own spin on the most timeless (and tiresome) of trans film stories: the coming out story.

Cybill Shepherd lends her voice as the narrator for this insightful documentary, which tells the story of acclaimed screenwriter and director Colin Higgins — the man behind classics like 9 to 5, Harold and Maude, and The Best Little Whorehouse in Texas. With wit and warmth, the film’s star-studded cast, including Jane Fonda, Dolly Parton, Lily Tomlin, Gene Wilder, and Goldie Hawn, share their memories of one of Hollywood’s sharpest comedic talents.

This laugh-out-loud shorts package has it all: dysfunctional families, Horny Hell, and Chucky (yes, that Chucky).

When bored and sexually frustrated Gen Zer, Elliot (Cooper Hoffman), lands his first real job assisting anti-woke art star Erika Tracy (Olivia Wilde), it isn't long before "erotic muse" and "sex slave" are added to his job description in legendary auteur Gregg Araki’s irreverent and entertaining sex comedy.

Starring, written, and directed by San Francisco’s own D’Arcy Drollinger, this riotous sequel to Shit & Champagne sees its titular dancing queen framed for her husband’s murder, leading to even more madcap hijinks — and now she’s back for the Opening Night of Frameline50!

Lining up a perfectly paired funny/sad comedy duo in Rachel Dratch and Jack Plotnick, writer/director Jason Laurits re-imagines Stephen King's Misery as a much gayer and much funnier tale of deranged fandom. When a washed-up TV personality is rescued from a car crash by his biggest (and only) fan, he thinks he’s been kidnapped, but maybe a kidnapping scandal is just the publicity he needs to get back on the map.

Seamlessly blending comedy and melodrama, writer/director John Early stars as Maddie Ralph, a dishwasher at an L.A. food content studio with dreams of being a chef and recipe creator despite her secret struggle with an eating disorder. Backed by alt-comedy mainstays Vanessa Bayer, Conner O’Malley, Kate Berlant, and more, Early’s portrayal of Maddie is as full of love as it is moving.

“I was born a good story,” announces Henry Cyril Paget, the next Marquess of Anglesey, as the opening credits roll in this fizzy historical biopic. Director Celyn Jones makes good on that promise in this drama starring Callum Scott Howells as the real-life figure whose flamboyance and determination to be his extravagant self creates a stir when he takes over his father’s Welsh estate.

“Space is big and freaky and full of dangerous shit.” Even with a dad who studies the stars for a living, Sheri has always been afraid of the cosmos — and meteors in particular. After she begins to have strange dreams that coincide with a meteor shower and a string of local disappearances, Sheri uncovers an otherworldly evil that dates all the way back to her father’s youth.

Elvira bets her husband Jack that she can bed her new friend Betsy by midnight or else Jack can make it with Betsy's husband Eddie in filmmaker Radley Metzger and screenwriter Jerry Douglas's classic sex comedy that puts the X in bisexual.

It’s a dingy bar bathroom and a cis guy with huge muscles is fucking you doggy style against the sink… Or maybe not… In Al’s cartoons, anything is possible, even if it's the furthest thing from reality. In truth, he’s an awkward trans guy who is completely in love with his oblivious best friend, Jesse, who happens to be his roommate at queer cartoonist camp.

Guided by Godard, styled like Araki, yet uniquely its own, Fergus Campbell’s debut feature is a charming exploration of youth told through the eyes of a bohemian group of misfits. Looking to escape the teenage wasteland known as Sparks, Nevada, they plan to go back in time through a mystical reservoir. At times melancholic, while other times hilariously bizarre, Sparks offers a visually striking and surreal journey worth hitching onto.

He/they underground filmmaker Henry Hanson presents a pair of bite-size features — Dog Movie and Puppygirl — exposing two of the greatest scourges facing trans people today: housing drama and puppygirls. Good girls and bad dogs only.

Jane Schoenbrun cements their place as one of cinema’s most vital auteurs with a psychosexual slasher that’s as ambitious as it is inventive. Starring Hannah Einbinder and Gillian Anderson, this riveting two-hander centers on a passionate writer who’s hired to reinvigorate their favorite horror franchise with the help of the original film’s now-reclusive final girl. But as the two women unravel the ways in which Camp Miasma has shaped them, they descend into a frenzied, blood-soaked world of desire, self-discovery, and delirium.