Jero receives an unexpected first anniversary gift from his boyfriend Tom — a breakup letter, accompanied with 299 more offering brutally honest reflections of their love affair, from their first hot Grindr hookup to reluctant romance. Jero is left to reexamine their entire relationship while navigating the post-break up waters in this playful and alluring romantic comedy.

In this bawdy and heartwarming story of mothers and sons, the trials of juggling self-care and caring for a loved one are told through Edward (James McArdle), a gay novelist looking after his non-verbal mother (Fionnula Flanagan). A chaotic weekend starts to unfold when his three best friends impulsively dump their elderly mothers onto him for a Pride getaway.

Laugh out loud with the classic Fun in Shorts program as this collection of films finds humor in dating, birthing alien babies, scamming your business to success, and cheesy baby gender reveal parties.

When the Straight White Maliens kidnap her ex, the titular sapphic monarch-to-be (voiced by Shabana Azeez) finds herself embarking on a truly zany journey through space. Filled with laugh-out-loud gay in-jokes, carabiner-tapping musical numbers, and offbeat characters, this year's Teddy Award winner is a lovably frenetic animated sci-fi comedy.

Some men are literal dogs! And Juan just so happens to find one in the wilderness while on vacation. He takes him in, bathes him, feeds him, and shows him much-needed affection. However, his girlfriend warns against becoming too attached… Director Marco Berger is back with a boldly absurdist fairy tale where animal desires and instincts turn strangely literal.

From devious revenge plots to invoking a demon to eat your ex boyfriends, this program of dark comedy films is designed for those that find joy in the demise of others.

If you’ve ever wondered what gender-swap teen comedies like She’s the Man would look like if they were actually made by trans and nonbinary folks, look no further! In She’s the He, two best friends concoct a plan to finally dispel the rumors that they’re gay: by coming out as trans women!

When two codependent besties suddenly find their house uninhabitable, a possible answer to all their problems appears in the form of a narcissistic space alien named Brian who favors track suits and loves a dance interlude. One mere sensual touch from Brian makes all of your anxieties and past traumas melt away. But is Brian's ulterior motive world domination?

Featuring Dylan O’Brien in a career-best turn, Twinless finds a charming odd couple pairing between straight Roman and gay Dennis, who meet at a support group for people who have lost their twin. A double prize winner at Sundance, James Sweeney's sophomore feature achieves a high-wire balancing act of laugh-out-loud comedy and gut-punching sadness, with filmmaking and storytelling sophistication to boot.

To celebrate the 25th anniversary of one of the definitive literary portraits of queer San Francisco, Michelle Tea’s Valencia, Frameline49 is hosting a screening of its radical, community-made 2013 film adaptation, followed by a walking tour of old haunts and dyke destinations of The Mission with Tea serving as your guide.

Three decades ago, SNL bravely dared to ask “Who’s he… or she?” and turned gender nonconformity into a punchline with Julia Sweeney's Pat. Now, a who’s-who of trans comics are tasked with the ultimate challenge: creating a new Pat sketch for 2025, while also interrogating the boneheadedly problematic (yet nonetheless meaningful) representation of our past along the way.